Allelic Variation and Selection in Effector Genes of Phytophthora infestans (Mont.) de Bary.
Identifieur interne : 000219 ( Main/Exploration ); précédent : 000218; suivant : 000220Allelic Variation and Selection in Effector Genes of Phytophthora infestans (Mont.) de Bary.
Auteurs : Juan G. Morales [Colombie] ; Astrid E. Gaviria [Colombie] ; Elizabeth Gilchrist [Colombie]Source :
- Pathogens (Basel, Switzerland) [ 2076-0817 ] ; 2020.
Abstract
Phytophthora infestans is a devastating plant pathogen in several crops such as potato (Solanum tuberosum), tomato (Solanum lycopersicum) and Andean fruits such as tree tomato (Solanum betaceum), lulo (Solanum quitoense), uchuva (Physalis peruviana) and wild species in the genus Solanum sp. Despite intense research performed around the world, P. infestans populations from Colombia, South America, are poorly understood. Of particular importance is knowledge about pathogen effector proteins, which are responsible for virulence. The present work was performed with the objective to analyze gene sequences coding for effector proteins of P. infestans from isolates collected from different hosts and geographical regions. Several genetic parameters, phylogenetic analyses and neutrality tests for non-synonymous and synonymous substitutions were calculated. Non-synonymous substitutions were identified for all genes that exhibited polymorphisms at the DNA level. Significant negative selection values were found for two genes (PITG_08994 and PITG_12737) suggesting active coevolution with the corresponding host resistance proteins. Implications for pathogen virulence mechanisms and disease management are discussed.
DOI: 10.3390/pathogens9070551
PubMed: 32659973
PubMed Central: PMC7400436
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Allelic Variation and Selection in Effector Genes of <i>Phytophthora infestans</i> (Mont.) de Bary.</title><author><name sortKey="Morales, Juan G" sort="Morales, Juan G" uniqKey="Morales J" first="Juan G" last="Morales">Juan G. Morales</name><affiliation wicri:level="1"><nlm:affiliation>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia</wicri:regionArea><wicri:noRegion>050034 Antioquia</wicri:noRegion></affiliation></author><author><name sortKey="Gaviria, Astrid E" sort="Gaviria, Astrid E" uniqKey="Gaviria A" first="Astrid E" last="Gaviria">Astrid E. Gaviria</name><affiliation wicri:level="1"><nlm:affiliation>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia</wicri:regionArea><wicri:noRegion>050034 Antioquia</wicri:noRegion></affiliation></author><author><name sortKey="Gilchrist, Elizabeth" sort="Gilchrist, Elizabeth" uniqKey="Gilchrist E" first="Elizabeth" last="Gilchrist">Elizabeth Gilchrist</name><affiliation wicri:level="1"><nlm:affiliation>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia</wicri:regionArea><wicri:noRegion>050034 Antioquia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Universidad EAFIT, 050034 Medellín, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Universidad EAFIT, 050034 Medellín</wicri:regionArea><wicri:noRegion>050034 Medellín</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32659973</idno><idno type="pmid">32659973</idno><idno type="doi">10.3390/pathogens9070551</idno><idno type="pmc">PMC7400436</idno><idno type="wicri:Area/Main/Corpus">000193</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000193</idno><idno type="wicri:Area/Main/Curation">000193</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000193</idno><idno type="wicri:Area/Main/Exploration">000193</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Allelic Variation and Selection in Effector Genes of <i>Phytophthora infestans</i> (Mont.) de Bary.</title><author><name sortKey="Morales, Juan G" sort="Morales, Juan G" uniqKey="Morales J" first="Juan G" last="Morales">Juan G. Morales</name><affiliation wicri:level="1"><nlm:affiliation>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia</wicri:regionArea><wicri:noRegion>050034 Antioquia</wicri:noRegion></affiliation></author><author><name sortKey="Gaviria, Astrid E" sort="Gaviria, Astrid E" uniqKey="Gaviria A" first="Astrid E" last="Gaviria">Astrid E. Gaviria</name><affiliation wicri:level="1"><nlm:affiliation>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia</wicri:regionArea><wicri:noRegion>050034 Antioquia</wicri:noRegion></affiliation></author><author><name sortKey="Gilchrist, Elizabeth" sort="Gilchrist, Elizabeth" uniqKey="Gilchrist E" first="Elizabeth" last="Gilchrist">Elizabeth Gilchrist</name><affiliation wicri:level="1"><nlm:affiliation>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia</wicri:regionArea><wicri:noRegion>050034 Antioquia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Universidad EAFIT, 050034 Medellín, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Universidad EAFIT, 050034 Medellín</wicri:regionArea><wicri:noRegion>050034 Medellín</wicri:noRegion></affiliation></author></analytic><series><title level="j">Pathogens (Basel, Switzerland)</title><idno type="ISSN">2076-0817</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><i>Phytophthora infestans</i> is a devastating plant pathogen in several crops such as potato (<i>Solanum tuberosum</i>), tomato (<i>Solanum lycopersicum</i>) and Andean fruits such as tree tomato (<i>Solanum betaceum</i>), lulo (<i>Solanum quitoense</i>), uchuva (<i>Physalis peruviana</i>) and wild species in the genus <i>Solanum</i> sp. Despite intense research performed around the world, <i>P. infestans</i> populations from Colombia, South America, are poorly understood. Of particular importance is knowledge about pathogen effector proteins, which are responsible for virulence. The present work was performed with the objective to analyze gene sequences coding for effector proteins of <i>P. infestans</i> from isolates collected from different hosts and geographical regions. Several genetic parameters, phylogenetic analyses and neutrality tests for non-synonymous and synonymous substitutions were calculated. Non-synonymous substitutions were identified for all genes that exhibited polymorphisms at the DNA level. Significant negative selection values were found for two genes (<i>PITG_08994</i> and <i>PITG_12737</i>) suggesting active coevolution with the corresponding host resistance proteins. Implications for pathogen virulence mechanisms and disease management are discussed.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">32659973</PMID><DateRevised><Year>2020</Year><Month>09</Month><Day>28</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Print">2076-0817</ISSN><JournalIssue CitedMedium="Print"><Volume>9</Volume><Issue>7</Issue><PubDate><Year>2020</Year><Month>Jul</Month><Day>09</Day></PubDate></JournalIssue><Title>Pathogens (Basel, Switzerland)</Title><ISOAbbreviation>Pathogens</ISOAbbreviation></Journal><ArticleTitle>Allelic Variation and Selection in Effector Genes of <i>Phytophthora infestans</i> (Mont.) de Bary.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">E551</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3390/pathogens9070551</ELocationID><Abstract><AbstractText><i>Phytophthora infestans</i> is a devastating plant pathogen in several crops such as potato (<i>Solanum tuberosum</i>), tomato (<i>Solanum lycopersicum</i>) and Andean fruits such as tree tomato (<i>Solanum betaceum</i>), lulo (<i>Solanum quitoense</i>), uchuva (<i>Physalis peruviana</i>) and wild species in the genus <i>Solanum</i> sp. Despite intense research performed around the world, <i>P. infestans</i> populations from Colombia, South America, are poorly understood. Of particular importance is knowledge about pathogen effector proteins, which are responsible for virulence. The present work was performed with the objective to analyze gene sequences coding for effector proteins of <i>P. infestans</i> from isolates collected from different hosts and geographical regions. Several genetic parameters, phylogenetic analyses and neutrality tests for non-synonymous and synonymous substitutions were calculated. Non-synonymous substitutions were identified for all genes that exhibited polymorphisms at the DNA level. Significant negative selection values were found for two genes (<i>PITG_08994</i> and <i>PITG_12737</i>) suggesting active coevolution with the corresponding host resistance proteins. Implications for pathogen virulence mechanisms and disease management are discussed.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Morales</LastName><ForeName>Juan G</ForeName><Initials>JG</Initials><Identifier Source="ORCID">0000-0001-5808-7872</Identifier><AffiliationInfo><Affiliation>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia, Colombia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gaviria</LastName><ForeName>Astrid E</ForeName><Initials>AE</Initials><AffiliationInfo><Affiliation>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia, Colombia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gilchrist</LastName><ForeName>Elizabeth</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Group and Laboratory of Fitotecnia Tropical, Departamento de Ciencias Agronómicas, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia sede Medellín, Medellín, 050034 Antioquia, Colombia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Universidad EAFIT, 050034 Medellín, Colombia.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>grant number code 111852128646, contract 0153-2012</GrantID><Agency>Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS)</Agency><Country></Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>07</Month><Day>09</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Pathogens</MedlineTA><NlmUniqueID>101596317</NlmUniqueID><ISSNLinking>2076-0817</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Phytophthora infestans sensu lato</Keyword><Keyword MajorTopicYN="N">Solanum spp.</Keyword><Keyword MajorTopicYN="N">effector proteins</Keyword><Keyword MajorTopicYN="N">evolutive selection</Keyword><Keyword MajorTopicYN="N">wild hosts</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>05</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>07</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>07</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>7</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>7</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>7</Month><Day>15</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32659973</ArticleId><ArticleId IdType="pii">pathogens9070551</ArticleId><ArticleId IdType="doi">10.3390/pathogens9070551</ArticleId><ArticleId IdType="pmc">PMC7400436</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Mol Plant Microbe Interact. 2007 Oct;20(10):1271-83</Citation><ArticleIdList><ArticleId IdType="pubmed">17918629</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Phytopathol. 2011;49:507-31</Citation><ArticleIdList><ArticleId IdType="pubmed">21663437</ArticleId></ArticleIdList></Reference><Reference><Citation>Trends Microbiol. 2004 Apr;12(4):148-54</Citation><ArticleIdList><ArticleId IdType="pubmed">15116722</ArticleId></ArticleIdList></Reference><Reference><Citation>Infect Genet Evol. 2013 Jul;17:123-31</Citation><ArticleIdList><ArticleId IdType="pubmed">23583792</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Evol. 1986 Sep;3(5):418-26</Citation><ArticleIdList><ArticleId IdType="pubmed">3444411</ArticleId></ArticleIdList></Reference><Reference><Citation>New Phytol. 2011 Aug;191(3):763-76</Citation><ArticleIdList><ArticleId IdType="pubmed">21539575</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 1994 Nov 11;22(22):4673-80</Citation><ArticleIdList><ArticleId IdType="pubmed">7984417</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioinformatics. 2007 May 15;23(10):1289-91</Citation><ArticleIdList><ArticleId IdType="pubmed">17379693</ArticleId></ArticleIdList></Reference><Reference><Citation>Genetics. 1993 Mar;133(3):693-709</Citation><ArticleIdList><ArticleId IdType="pubmed">8454210</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2010 May 25;107(21):9909-14</Citation><ArticleIdList><ArticleId IdType="pubmed">20457921</ArticleId></ArticleIdList></Reference><Reference><Citation>Immunogenetics. 2008 Sep;60(9):495-506</Citation><ArticleIdList><ArticleId IdType="pubmed">18581108</ArticleId></ArticleIdList></Reference><Reference><Citation>Evol Appl. 2018 May 09;11(8):1342-1353</Citation><ArticleIdList><ArticleId IdType="pubmed">30151044</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Evol. 2018 Jun 1;35(6):1547-1549</Citation><ArticleIdList><ArticleId IdType="pubmed">29722887</ArticleId></ArticleIdList></Reference><Reference><Citation>Genetics. 2004 Jul;167(3):1341-60</Citation><ArticleIdList><ArticleId IdType="pubmed">15280247</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2004 Dec 10;306(5703):1957-60</Citation><ArticleIdList><ArticleId IdType="pubmed">15591208</ArticleId></ArticleIdList></Reference><Reference><Citation>mBio. 2018 Aug 28;9(4):</Citation><ArticleIdList><ArticleId IdType="pubmed">30154258</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant. 2016 May 2;9(5):636-638</Citation><ArticleIdList><ArticleId IdType="pubmed">27095376</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioinformatics. 2009 Jun 1;25(11):1451-2</Citation><ArticleIdList><ArticleId IdType="pubmed">19346325</ArticleId></ArticleIdList></Reference><Reference><Citation>Phytopathology. 2009 Jan;99(1):82-8</Citation><ArticleIdList><ArticleId IdType="pubmed">19055438</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Evol. 2000 Jan;17(1):32-43</Citation><ArticleIdList><ArticleId IdType="pubmed">10666704</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell. 2007 Aug;19(8):2349-69</Citation><ArticleIdList><ArticleId IdType="pubmed">17675403</ArticleId></ArticleIdList></Reference><Reference><Citation>Front Plant Sci. 2016 May 27;7:672</Citation><ArticleIdList><ArticleId IdType="pubmed">27303410</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Pathog. 2014 Apr 24;10(4):e1004057</Citation><ArticleIdList><ArticleId IdType="pubmed">24763622</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Microbe Interact. 2009 Jun;22(6):630-41</Citation><ArticleIdList><ArticleId IdType="pubmed">19445588</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Opin Plant Biol. 2000 Aug;3(4):299-304</Citation><ArticleIdList><ArticleId IdType="pubmed">10873849</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2008 Aug 06;3(8):e2875</Citation><ArticleIdList><ArticleId IdType="pubmed">18682852</ArticleId></ArticleIdList></Reference><Reference><Citation>J Bacteriol. 2006 Feb;188(4):1405-10</Citation><ArticleIdList><ArticleId IdType="pubmed">16452423</ArticleId></ArticleIdList></Reference><Reference><Citation>Sci Rep. 2017 Feb 10;7:42338</Citation><ArticleIdList><ArticleId IdType="pubmed">28186158</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell. 2005 Jun;17(6):1839-50</Citation><ArticleIdList><ArticleId IdType="pubmed">15894715</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2012 Aug;40(15):e115</Citation><ArticleIdList><ArticleId IdType="pubmed">22730293</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Pathol. 2011 Jan;12(1):93-102</Citation><ArticleIdList><ArticleId IdType="pubmed">21118351</ArticleId></ArticleIdList></Reference><Reference><Citation>Genetics. 1996 Nov;144(3):1005-13</Citation><ArticleIdList><ArticleId IdType="pubmed">8913745</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2005 May 24;102(21):7766-71</Citation><ArticleIdList><ArticleId IdType="pubmed">15894622</ArticleId></ArticleIdList></Reference><Reference><Citation>Stud Mycol. 2018 Mar;89:105-115</Citation><ArticleIdList><ArticleId IdType="pubmed">29910517</ArticleId></ArticleIdList></Reference><Reference><Citation>Protein Eng Des Sel. 2008 Jan;21(1):37-44</Citation><ArticleIdList><ArticleId IdType="pubmed">18096555</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Pathog. 2012;8(10):e1002940</Citation><ArticleIdList><ArticleId IdType="pubmed">23055926</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Microbe Interact. 2015 Oct;28(10):1063-72</Citation><ArticleIdList><ArticleId IdType="pubmed">26125490</ArticleId></ArticleIdList></Reference><Reference><Citation>Phytopathology. 2001 Oct;91(10):956-65</Citation><ArticleIdList><ArticleId IdType="pubmed">18944122</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2007 Nov 1;450(7166):115-8</Citation><ArticleIdList><ArticleId IdType="pubmed">17914356</ArticleId></ArticleIdList></Reference><Reference><Citation>Stud Mycol. 2018 Mar;89:85-93</Citation><ArticleIdList><ArticleId IdType="pubmed">29910515</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Opin Plant Biol. 2008 Aug;11(4):373-9</Citation><ArticleIdList><ArticleId IdType="pubmed">18511334</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Opin Microbiol. 2016 Dec;34:127-135</Citation><ArticleIdList><ArticleId IdType="pubmed">27723513</ArticleId></ArticleIdList></Reference><Reference><Citation>Microbiol Spectr. 2016 Dec;4(6):</Citation><ArticleIdList><ArticleId IdType="pubmed">28087929</ArticleId></ArticleIdList></Reference><Reference><Citation>Appl Environ Microbiol. 2008 May;74(10):3171-81</Citation><ArticleIdList><ArticleId IdType="pubmed">18378665</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Evol. 2005 Mar;22(3):659-72</Citation><ArticleIdList><ArticleId IdType="pubmed">15548752</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2009 Sep 17;461(7262):393-8</Citation><ArticleIdList><ArticleId IdType="pubmed">19741609</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Pathog. 2006 May;2(5):e50</Citation><ArticleIdList><ArticleId IdType="pubmed">16733545</ArticleId></ArticleIdList></Reference><Reference><Citation>Evolution. 1985 Jul;39(4):783-791</Citation><ArticleIdList><ArticleId IdType="pubmed">28561359</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13429-34</Citation><ArticleIdList><ArticleId IdType="pubmed">8917608</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Phytopathol. 2014;52:551-81</Citation><ArticleIdList><ArticleId IdType="pubmed">25001453</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Opin Plant Biol. 2018 Aug;44:108-116</Citation><ArticleIdList><ArticleId IdType="pubmed">29604609</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Colombie</li></country></list><tree><country name="Colombie"><noRegion><name sortKey="Morales, Juan G" sort="Morales, Juan G" uniqKey="Morales J" first="Juan G" last="Morales">Juan G. Morales</name></noRegion><name sortKey="Gaviria, Astrid E" sort="Gaviria, Astrid E" uniqKey="Gaviria A" first="Astrid E" last="Gaviria">Astrid E. Gaviria</name><name sortKey="Gilchrist, Elizabeth" sort="Gilchrist, Elizabeth" uniqKey="Gilchrist E" first="Elizabeth" last="Gilchrist">Elizabeth Gilchrist</name><name sortKey="Gilchrist, Elizabeth" sort="Gilchrist, Elizabeth" uniqKey="Gilchrist E" first="Elizabeth" last="Gilchrist">Elizabeth Gilchrist</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PlantPathoEffV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000219 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000219 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= PlantPathoEffV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:32659973
|texte= Allelic Variation and Selection in Effector Genes of Phytophthora infestans (Mont.) de Bary.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32659973" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a PlantPathoEffV1
| This area was generated with Dilib version V0.6.38. |  |